Indications and usage:it is a hepatitis c virus (hcv) nucleotide analog ns5b polymerase inhibitor indicated for the treatment of chronic hepatitis c (chc) infection as a component of a combination antiviral treatment regimen.*efficacy has been established in subjects with hcv genotype 1, 2, 3 or 4 infection, including those with hepatocellular carcinoma meeting milan criteria (awaiting liver transplantation) and those with hcv/hiv-1 co-infection.*dosage and administration:* one 400 mg tablet taken once daily with or without food.* should be used in combination with ribavirin or in combination with pegylated interferon and ribavirin for the treatment of chc.recommended combination therapy:hcv mono-infected and hcv/hiv-1 co-infected treatment durationgenotype 1 or 4 sovaldi + peg-interferon alfa + ribavirin 12 weeksgenotype 2 so
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