Description flupentixol is an antipsychotic neuroleptic drug. it is a thioxanthene, and therefore closely related to the phenothiazines. its primary use is as a long acting injection given two or three weekly to people with schizophrenia who have a poor compliance with medication and suffer frequent relapses of illness. it is a d1 and d2 receptor antagonist. it is not approved in the united states.indication for use in the treatment of schizophrenia and depressionmechanism of action flupenthixol is a thioxanthene antipsychotic. the mechanism of action of flupenthixol is not completely understood. flupenthixol is a powerful antagonist of both d1 and d2 dopamine receptors, and an alpha-adrenergic receptor antagonist. it s antipsychotic activity is thought to be related to blocks postsynaptic dopamine receptors in the cns.
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