About diclofenac potassiumsnsaid, anti-inflammatory ,antipyretic and analgesic.ssmechanism of action of diclofenac potassiumsdiclofenac possess analgesic, anti-inflammatory and antipyretic action. it inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of prostaglandins (((pgs))). it is more potent against cyclo-oxygenase-2 enzyme as compared to other nsaids like indomethacin, naproxen etc. it reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.ssindications for diclofenac potassiums1.rheumatoid arthritis s2.ankylosing spondylitis s3.acute gout s4.joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints s5.osteoarthritis s6.for the relief of pain and inflammation in dental minor surgery and orthopedic s7.dysmenorrhoea
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