About ceftriaxonethird generation cephalosporin antibiotic(parenteral).mechanism of action of ceftriaxoneceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like ceftriaxone. ssindications for ceftriaxones1.meningitis s2.septicaemia s3.typhoid s4.uti s5.prophylaxis in surgical infections s6.lower respiratory tract infections s7.pneumonia s8.pelvic inflammatory disease s9.std s10.bacteraemia
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