About cefalexina first-generation cephalosporin antibiotic.mechanism of action cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like cephalexin indications for cefalexin1.respiratory tract infections 2.urinary tract infections 3.surgical prophylaxis 4.skin infections` 5.joint & bone infections 6.otitis media` 7.reproductive tract infections` contra-indications1.hypersensitivity to cephalosporins 2.porphyria 3.neuromuscular disorders.
Voir plus de détails