This medication is used to treat hemorrhoids and itching/swelling in the rectum and anus. it is also used with other medications to treat certain intestinal problems (such as ulcerative colitis of the rectum and other rectal/anal inflammatory conditions). hydrocortisone suppositories help to relieve rectal pain, itching, bloody diarrhea, and bleeding by reducing swelling (inflammation) directly in the rectum and anus. hydrocortisone belongs to a class of drugs called corticosteroids.hydrocortisone acetate rect may interact with the following medicationssevere interactions of hydrocortisone acetate rect:these medications are not usually taken together. immunosuppressives- immunomodulatorssystemic corticosteroids/live vaccinescorticosteroids- corticotropin (acth)/amphotericin bglucocorticoids/aldesleukincorticosteroids/mifepristonecorticosteroids/selected anticholinesterase
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