About trimebutineantimuscarinic, a noncompetitive spasmolytic agent, in irritable bowel syndrome (spastic colon).mechanism of action of trimebutinetrimebutine is a noncompetitive spasmolytic agent. it slows down the movement of the bowel and therefore it is used for the treatment of irritable bowel syndrome.indications for trimebutine1.irritable bowel syndrometypical dosage for trimebutineoral adult:600 mg/day in 2 - 3 divided doses before mealsstorage requirements for trimebutine
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