About cefadroxilfirst generation cephalosporin, para-hydroxy derivative of cefalexin, oral broad-spectrum antibioticmechanism of action cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like cefadroxil indications for cefadroxil1. urinay tract infections 2. tonsillitis & pharyngitis 3. skin &soft tissue infections 4. otitis media. contra-indications of cefadroxil1.hypersensitivity to cephalosporins 2.porphyria 3.neuromuscular disorders.
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