About mebeverinereserpine derivative, antimuscarinic, a musculotropic antispasmodic, motility stimulant.mechanism of action of mebeverinemebeverine has a direct relaxant effect on smooth muscle. this will inhibits gastrointestinal propulsive motility and gastric acid secretion.indications for mebeverine1.irritable bowel syndrometypical dosage for mebeverineadult: 405 mg / day in 3- divided doses to be taken 20 minutes before meals. dose can be gradually reduced after 1 week if sufficient response is obtained. children above 10 years: 405 mg / day in 3- divided doses to be taken 20 minutes before meals. dose can be gradually reduced after 1 week if sufficient response is obtained. children below 10 years: contraindicated.
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