About dipyridamolesantiplatelet agent(platelet aggregation inhibitor), vasodilator.ssmechanism of action of dipyridamolesthe drug exerts it`s antithrombotic action by interfering with platelet aggregation. it inhibits phosphodiesterase, blocks uptake and degradation of adenosine (local mediator involved in auto regulation of coronary blood flow in response to ischaemia.), potentiate prostacyclin (pg i2) and increase cyclic amp in platelets and interferes with aggregation.ssindications for dipyridamoles1. thromboembolic disorders s2. angina pectoris s3. inhibition of platelet adhesion in patients with prosthetic heart valves ssinteractions for dipyridamolesoral anti-coagulants & anti-arrhythmic agent adenosine: efficacy enhanced by dipyridamole. santacids: reduces efficacy of dipyridamole. saminophylline: reverses vasodilatation effect of dipyridamole. saspirin: useful combination for prevention of thromboembolic phenomenon.
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