About sodium cromoglycatesynthetic chromone derivative, mast cell stabilizer, antiallergic, asthma prophylactic.mechanism of action of sodium cromoglycatethis synthetic chromone derivative has several mechanism of action 1. it is a mast cell stabilizer 2. it inhibit chloride channels and inhibit the exaggerated neuronal reflexes triggered by stimulation of irritant receptors on sensory nerve endings (e.g. exercise-induced asthma) and release of preformed cytokines from several type of inflammatory cells (t-cell, eosinophil) in allergen-induced asthma.3. it inhibit calcium influx of the cell 4.it inhibit the enzyme phosphodiesterase 5. it reduce alpha-adrenoreceptor density 6. it inhibit ig-e dependant secretion of cells other than mast cells.
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